Publications

Microbial ecology. 2010-11-01; 60.4: 721-9.

Comparative genome analysis of Prevotella ruminicola and Prevotella bryantii: insights into their environmental niche

Cann IK, Mackie RI, White BA, Forsberg CW, Mongodin E, Daugherty S, Russell JB, Wilson DB, Nelson WC, Nelson KE, Morrison M

PMID: 20585943

Abstract

The Prevotellas comprise a diverse group of bacteria that has received surprisingly limited attention at the whole genome-sequencing level. In this communication, we present the comparative analysis of the genomes of Prevotella ruminicola 23 (GenBank: CP002006) and Prevotella bryantii B(1)4 (GenBank: ADWO00000000), two gastrointestinal isolates. Both P. ruminicola and P. bryantii have acquired an extensive repertoire of glycoside hydrolases that are targeted towards non-cellulosic polysaccharides, especially GH43 bifunctional enzymes. Our analysis demonstrates the diversity of this genus. The results from these analyses highlight their role in the gastrointestinal tract, and provide a template for additional work on genetic characterization of these species.

Metrics