Publications

BMC bioinformatics. 2010-09-10; 11.457.

An algorithm for automated closure during assembly

Koren S, Miller JR, Walenz BP, Sutton G

PMID: 20831800

Abstract

Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can involve targeted sequencing. Finishing reads may be incorporated by manual or automated means. One automated method uses targeted addition by local re-assembly of gap regions. An obvious alternative uses de novo assembly of all the reads.

Metrics