Publications

Critical care (London, England). 2025-07-03; 29.1: 275.

Longitudinal analysis of lung microbiome, immune response, and metabolism in ventilator-associated pneumonia: a cohort study

Bustos IG, Serrano-Mayorga CC, Guerrero JL, Baker JM, Brown C, Falkowski N, Ranjan P, Acosta-Gonzalez A, Mendez LM, Garcia-Cordoba A, Echeverry-Gutierrez A, Bojaca DA, Chisica-Mahecha M, Guarin-Tequia N, Romero-Romero L, Gonzalez-Juarbe N, Rodriguez A, Cala MP, Martin-Loeches I, Chotirmall SH, Dickson RP, Reyes LF

PMID: 40611327

Abstract

 Ventilator-associated pneumonia (VAP) is a common complication in patients under invasive mechanical ventilation (IMV), yet its underlying mechanisms remain poorly understood. This study investigated the lung microbiome, inflammatory response, and metabolism in patients undergoing IMV to identify factors that may predispose them to developing VAP.

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