Publications

BMC microbiology. 2011-09-26; 11.213.

The protein interaction map of bacteriophage lambda

Rajagopala SV, Casjens S, Uetz P

PMID: 21943085

Abstract

Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins. We have manually curated the lambda literature and compiled a total of 33 interactions that have been found among lambda proteins. We set out to find out how many protein-protein interactions remain to be found in this phage.

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